Production of Medicinal Cream and Ointments
Pharmacy preparations to treat conditions such as rashes, skin irritation, itching, fungal infections, etc. they are usually supplied in the form of cream or ointment as this provides effective ways to bring the active ingredient directly to the required area. Products can be water in oil (w / o) or liquid oil (o / w) emulsion, which includes waxes, emollients, and lubricants dispersed in the oil phase, and a water phase containing emulsifying, stabilizing, and thickening agents, preservatives. and in some cases, color. The active ingredients are dispersed in any phase or added when the emulsion is formed and allowed to cool.
The process
The ingredients, composition, and viscosity of the product vary greatly, however, the standard production process is divided into four functions each:
Oil phase adjustment. Flake/powder ingredients, sometimes dried prematurely, are dissolved in mineral oil or silicone oil. Heating may be necessary to dissolve other ingredients.
Hydration of aqueous phase ingredients. Emulsifiers, thickeners, and stabilizers are dispersed in water on a separate vessel. Heat may be needed to speed up the flow of water.
Forming Emulsion. These two phases are combined under intense stirring to form an emulsion.
Dispersion of Active Ingredient. The active ingredient usually makes up a small portion of the composition; this should be well dispersed to increase productivity and productivity.
The problem
Using common agitators can be met:
When added to water, solidification, solidification, and emulsifying ingredients can form agglomerates that agitators can break down.
Similarly, the ingredients of the oil phase can form lumps that need to be cut to disperse.
Ingredients must be fully hydrated to obtain the required viscosity and improve yield.
Slightly submerged materials can form on the wall of the vessel, tank baffles, and parts of the agitator.
Agitators cannot adequately reduce the droplet size to form a stable emulsion.
Active ingredients can be sensitive to heat. Cooling the product before adding the active ingredient increases the processing time.
Improper distribution of active ingredients interferes with product efficiency.
Longer mixing times and additional equipment may be required to obtain a balanced and stable finished product.
Solution
Wahal Engineer mixer can quickly dissolve solids into liquids, hydrate thickening and stabilizing agents, break down agglomerates, and effectively reduce particle and globule size to form stable emulsions and solvents. Mixing times are greatly reduced, while product consistency and consistency are greatly improved. This is achieved as follows:
Stage 1
Rotating the large rotary speed inside the work head creates a strong absorption that pulls the solid and solid ingredients up from the bottom of the vessel to the tip of the work.
Stage 2
Centrifugal force takes the lead to the surrounding area of the work head where the agglomerates are separated by a mechanical gap between the tips of the rotor blades and the inner wall of the stator. The product is then forced out of the stator and distributed to the body of the mixture. At the same time, new items are being pulled from the job title.
Stage 3
The insertion and expulsion of the ingredients by the work headsets the rotation pattern for mixing on the vessel. All ingredients exceed the job title several times in a short mixing cycle, which gradually reduces the particle size, and ensures that the final product is aggressive, stable, and balanced.
We have Pharmaceutical manufacturing Plant Machinery are :
Industrial agitators sanitizer machine | High Shear Mixer | Sanitizer Machine | Powder Induction Machine | High Speed Powder Induction | Liquid Powder Mixers
